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Description

combined icaritin with doxorubicin in a codelivery system to trigger potent immunogenic cell death, which further induced robust immunity and significantly repressed HCC progression [214]

Ultimately, these debates converge on a central translational question: is ROS itself a druggable target, as evidenced by the success of ROS-inducing chemo-immunotherapies [222,223,224,225] and nanomedicines [278, 291, 335], or is its true utility as a predictive biomarker for patient stratification [235, 236]

Epub 2010 Feb 9

These alterations are associated with increased levels of THs binding protein levels, upregulation of DIO1 and 2 activities and downregulation of DIO3