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The role of exogenous antioxidants in preventing or delaying oxidative damage has become increasingly controversial [287]

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An investigation from Farshbaf-Khalili et al., in Iran (2022), in a triple-blind, randomized controlled trial, examined the effects of curcumin on oxidative stress markers in postmenopausal women 4060 years of age

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FIGURE 4 While spin traps and nitroxides may possess significant therapeutic potential, their clinical applications may be limited by poor bioavailability and targeting and inadequate BBB penetration (mainly due to low lipophilicity)

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