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Increased expression of the copper efflux transporter ATP7A mediates resistance to cisplatin, carboplatin, and oxaliplatin in ovarian cancer cells

In addition, ten genes (such as anti-ACSL3 antibody (ACSL3), GPX4, and SLC7A11) associated with ferroptosis have been postulated to have regulatory roles in lung adenocarcinoma (15)

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In the final step to the coenzyme, CobC removes the 5' phosphate group: [32] [33] Adenosylcobalamin-5'-phosphate + H 2 O adenosylcobalamin + phosphate The complete biosynthetic route involves a long linear path that requires about 25 contributing enzyme steps