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Efficacy and Interaction of Antioxidant Supplements as Adjuvant Therapy in Cancer Treatment: A Systematic Review

Although high selectivity of PAG for CSE over CBS has been reported (i.e., an IC 50 of 40 M for the CSE-catalyzed reaction using 1 mM of cysteine as the substrate, with no detectable inhibition of CBS even at 10 mM PAG), it also inhibits several other PLP enzymes, such as aspartate aminotransferase, alanine aminotransferase, and methionine -lyase (Sun et al., 2009)

181 : 16611672 Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, Wang X

However, comprehensive clinical trials specifically examining glutathione use during breastfeeding are limited