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ncRNAs are a diverse group of RNA molecules that do not encode proteins but play crucial roles in regulating gene expression and various cellular processes [152, 153]

Osteoprogenitor cells, but not mature osteoblasts/osteocytes that support AML growth in the bone marrow microenvironment

Most mutations (including the p.Gly376Asp) promote cytoplasmic mislocalization [20] and formation of toxic protein aggregates [21], coupled to a depletion TDP-43 in the nucleus that causes a loss of the nuclear function of the protein [22]

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