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What to consider if your results are out of range: If you're low in folate, increase your intake of naturally folate-rich foods such as spinach and other dark greens, asparagus, Brussels sprouts, avocado, black-eyed peas and other legumes, and citrus fruits

The most common concentrations include 2.5mg/mL (typically in smaller 1 mL vials containing 2.5 mg total), 5mg/mL (in 1 mL vials containing 5 mg total or 2 mL vials containing 10 mg total), and occasionally higher concentrations for patients on maintenance doses

One possible explanation is that low serum vitamin B12 levels would trap folate as 5-methyltetrahydrofolate, prevent the generation of methionine from homocysteine, and therefore reduce protein synthesis and lean tissue deposition

Individual reactions can vary based on personal health conditions and concurrent medications, and human long-term safety data are limited because no large clinical trials have been completed