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When the gut lining is inflamed and damaged, the gut lining is more porous than it should be

Upregulation of BKN and histamine by estrogen in combination with hypomethylation (mild increase in homocysteine) may be linked to the pathogenesis of high flow in female dominated POTS, SIBO, MCAS, and EDS

These properties enable bilirubin to neutralize reactive oxygen species, reduce inflammation, and inhibit the progression of fibrosis, all of which are key factors in the pathogenesis of MASLD[34-36]

A healthcare professional will advise how often injections are needed to maintain healthy levels. The timing depends on deficiency severity, symptoms, and blood test results