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Missed Dosage If you miss a scheduled dose: Do not double the next dose Follow your providers instructions for rescheduling Contact your provider or pharmacy if you are unsure how to proceed Storage Store refrigerated as directed on the pharmacy label Protect from light Do not freeze Keep out of reach of children Medication Disposal Dispose of unused or expired medication according to local medication disposal guidelines

Contrastingly, unchanged symptomatology or clinical deterioration was observed in the patients whose treatment regimen remained unchanged after HA detection

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The hemodynamic profile may evolve from an early hyperdynamic state (characterized by high cardiac output and low systemic vascular resistance) to a late hypodynamic state (with low cardiac output) in advanced shock, with microcirculatory dysfunction exacerbating myocardial ischemia and injury (11, 12)