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Use conservative peptide dosing (5070% of standalone effective dose) and avoid concurrent antidepressant dose escalation

Methotrexate and its mechanisms of action in inflammatory arthritis

Therapeutic modulation of the microbiome shows promise: antibiotics targeting dysbiotic bacteria and fecal microbiota transfer (FMT) reduce lesion growth in preclinical models, while probiotics restoring Lactobacillus dominance improve NK cell activity and reproductive outcomes