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participates in the conjugation and elimination of compounds supports natural detoxification pathways promotes a perception of metabolic lightness Immunity and protection of defense system cells Immune cells are sensitive to redox status

Only human studies were considered, with quasi-RCTs, non-RCTs, case series, conference manuscript, editorials, posters, and unreliable data excluded

doi:10.1371/journal.ppat.1006286 23

Biochem De Biophys Acta Gen Subj 1760:10881095 El-Mahmoudy A, Matsuyama H, Borgan MA, Shimizu Y, El-Sayed MG, Minamoto N, Takewaki T (2002) Thymoquinone suppresses expression of inducible nitric oxide synthase in rat macrophages