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While molecular mechanisms underlying ICD have been extensively studied, the clinical implications of ICD in disease classification, treatment, and prognosis remain underexplored

The expression levels of ACSL4 and NCOA4 were significantly upregulated, whereas GPX4 expression remained relatively stable without significant changes

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Within the small cavities (follicles) of the thyroid, tyrosine (an amino acid that serves as the building block for thyroid hormone production) combines with iodide through a process called iodination, to create several thyroid hormones: T1, T2, T3, T4