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POI is rare, however, as only about 1% of women under 44 experience POI

They consist of cigarette manufacturers, which have an incentive to either enter the e-cig market themselves, suppress competition from upstart e-cig manufacturers, or both. They are joined by Pharmaceutical companies that make NRT productsThey have benefitted from government encouragement that smokers use their products to aid in smoking cessation and government limitations on information on tobacco harm reduction through the use of e-cigs or smokeless tobacco products