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118 OkazakiH.MatsunagaN.FujiokaT.OkazakiF.AkagawaY.TsurudomeY.et al (2014)

Chappell D, Hofmann-Kiefer K, Jacob M, Rehm M, Briegel J, Welsch U, Conzen P, Becker BF

Extracted ion LC-MS chromatograms (m/z 1183.61184.1) of insulin-SF MH55+ in (A) unmodified insulin (20 g/ml) in human plasma control and (B) human plasma incubated with insulin (20 g/ml) and 50 M SF for 4 h at 37C, showing the appearance of two different insulin-SF conjugates at retention times of 6.46 and 7.08 min