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Tofersen: first approval

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doi:10.1016/j.biochi.2016.08.002

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Natural compounds or TCM formulas with ferroptosis-inhibitory effects in other kidney diseases [e.g., berberine and irisflorentin (201, 202)] have not been tested in LN, representing an untapped therapeutic avenue

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MEIS TFs, though largely ubiquitous, are selectively guided to cardiac-specific enhancers by binding with lineage-enriched TFs

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