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B: However, in the endothelial cells with high level of phosphor AKT, following the block of VEGF stimulation, the AKT pathway remains active inducing transcription of FGF, an angiogenic factor, which on one side promotes endothelium proliferation and on the other further phosphorylates AKT producing a positive loop

Additionally, formalin-fixed, paraffin-embedded (FFPE) tissue samples of peritumoral tissue from five non-chronic lung disease patients were provided by the CPC-M bioArchive (Comprehensive Pneumology Center, Helmholtz Munich)

These findings not only deepen our understanding of the role of ferroptosis in radiotherapy, but also provide a scientific basis for developing new therapeutic strategies

doi: 10.1186/s12951-022-01395-9 160 ZhangBSuXKangJChenL