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In contrast, LDH-B transform lactate into pyruvate, allowing cells to use lactate as a source of nutrients for oxidative metabolism ( ( Figure 1 ) ( An increase of LDH-A expression is key in the metabolism of cancer cells and is considered a negative prognostic biomarker ( D-lactate is derived from carbohydrate metabolism and lipids through the formation of methylglyoxal (MG) ( ( Figure 2 )

Diclofenac sodium, a non-steroidal anti-inflammatory drug (NSAID), is effective in reducing inflammation, pain, and swelling, providing a dual-action formulation that addresses both the symptoms and underlying causes of pain

Electrophilic properties of itaconate and derivatives regulate the IB-ATF3 inflammatory axis