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Change history 30 July 2025 This paper was originally published under Creative Commons Attribution 4.0 International license, CC-BY-NC-ND, The Author(s)

The enormous selective advantage of red blood cells with normal hemoglobin or anti-sickling hemoglobin predicts that genetic modification of a proportion of HSCs (estimated 1020%) may suffice as a one-off treatment (ClincialTrials.gov Identifier: NCT02963064)

Lovastatin stimulates up-regulation of 7 nicotinic receptors in cultured neurons without cholesterol dependency, a mechanism involving production of the alpha-form of secreted amyloid precursor protein

While further data is needed to identify dose, frequency, and appropriate age group, intranasal oxytocin may offer some benefit to patients with ASD