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Choline Deficiency - 89% of pregnant women Only 11% of pregnant women meet recommended choline intake Even worse for vegetarian/vegan diets (only 7% adequate) Choline essential for liver function and methylation Deficiency increases susceptibility to hepatic injury Other Risk Factors Low sulfur amino acid intake (vegetarian/vegan diets) Blood sugar dysregulation Chronic infections Chemical exposures (chlorine, formaldehyde, VOCs) Genetic variants (CBS, CYP2E1, MTHFR, GSTM1/GSTT1) Obesity and metabolic syndrome The Postnatal Risk: Tylenol After Vaccination If prenatal acetaminophen creates vulnerability during fetal brain development, post-vaccination acetaminophen in infants may represent the final burden on an already compromised system

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Less studied is the observation that fibroblasts from AD patients show altered expression of EAAT1 amino acid transporter, with the degree of alteration correlating with dementia severity [555]