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Avoid use while pregnant or nursing

4 To extend your lifespan and reduce cancer risk, aim for an IGF-1 level that's low, but not too lowespecially after age 75, when IGF-1 is essential for maintaining bone, brain, and muscle health

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Once in the brain, achieving neuron- or microglia-specific targeting, mitigating any neuroinflammatory side effects, and ensuring biodegradable or clearable designs are critical for clinical advancement