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Most recently another controlled trial of prasinezumab (PADOVA), which had enrolled subjects with more advanced disease compared to the initial trial and randomised subjects to 4-weekly iv injections of 1500 mg prasinezumab or placebo for at least 76 weeks, used time to 5-point worsening on MDS-UPDRS part III scores as primary outcome measure

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A similar trend is observed in inter-observer validity and intra-observer validity between two modalities (SEC and slit photo) as well as between two observers (Table 1