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On day 7 seedlings were transferred to fresh growth medium, and then some of the plates were supplemented with AITC to a final concentration of 1 mM whereas others remained non-treated (control)

In addition to these findings, in vivo evidence of IgG1-3 pathogenicity is provided by a model in which a mouse knockout of murine IgG1-equivalent to human IgG4-developed myasthenic features when immunized against MuSK

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