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Description

As an alternative, current models for studying the infant gut barrier include cell lines, enteroids and animal models

Research models cover traumatic brain injury, hippocampal ischemia, cuprizone-induced demyelination (a multiple sclerosis model), and spinal cord compression injury with tail paralysis

Peritendinous injection targets tissue with poor blood supply

A reasonable bar would be at least one phase 2 RCT in a clinically relevant population (cognitive impairment, mild Alzheimer disease, post-stroke recovery, or similar) showing clinical efficacy with acceptable safety