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Understanding disease mechanisms Artificial intelligence has been applied to analyze epigenomic and transcriptomic data, identifying changes in genes involved in neuronal inflammation and mitochondrial functions

10.1016/j.yebeh.2020.107608 55

In Alzheimers disease, PHGDH upregulation, an upstream control point in the serine synthesis pathway, supports the idea that disrupted serine metabolism is coupled to persistent neuroinflammatory signaling 73