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Adv Gerontol 2022;12:1438

The trial proceeded without reported toxicity, and no lethal dose threshold (LD1) was ever established in subsequent safety testing meaning researchers administering the compound could not find a dose that caused death in even 1% of test subjects across the animal model safety work that preceded and followed the human study

Within synaptic vesicles, amphetamine disrupts vesicular monoamine storage through two complementary mechanisms: (A) diffusion into vesicles and proton buffering, which collapses the vesicular proton gradient required for vesicular monoamine transporter 2 (VMAT2) function

Both chemical sensitivity and MTHFR challenges stem from the same fundamental issue: cellular processing capacity