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Human umbilical cord mesenchymal stem cell-derived extracellular vesicles: a novel therapeutic paradigm

Long-term use may lead to reduced efficacy and increased adverse effects (Xu et al., 2023)

Fatty acid fragments such as pimelic and especially azelaic acids (C 7 and C 9 dicarboxylic acids, respectively) are generated from hydroperoxy fatty acids of the 9-LOX pathway with aldehydes, and these may be involved in systemic acquired resistance and the defence against pathogens