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Sulforaphane, through its ability to activate the Nrf2 pathway, enhances the production of antioxidant enzymes, effectively combating oxidative stress and protecting neurons from damage

The peptides interaction with IGF-binding proteins is diminished by its altered structure, which includes a longer chain and changed binding characteristics

For instance, ACSL4 promotes the incorporation of PUFAs into phospholipids, making them vulnerable to lipoxygenase (ALOX)-mediated oxidation, which compromises the lipid bilayer and induces ferroptosis [17, 18]

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