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i-j , Fluorescence histograms of FSP1 GFP-P2A-BFP cells grown in normal or vitamin B2-deficient medium for 72 h showing changes in GFP:BFP ratio ( i ) or GFP and BFP fluorescence ( j )

10.1038/s41537-017-0037-1 146 OngW

Biodegradable nanoplatform upregulates tumor microenvironment acidity for enhanced cancer therapy via synergistic induction of apoptosis, ferroptosis, and anti-angiogenesis

however substantial glutathionylation of non-pathogenic SOD1 WT compared to the aggressive variant SOD1 V148G , suggested that this modification alone is not predictive of disease progression