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It is noteworthy that NQO1 has been implicated in the bioreduction of various nitroheterocyclic compounds, which is essential for inducing their anticancer activities

The segmental duplications are observed in different chromosomes whereas tandem duplications occur in the same chromosome (Liu et al., 2011)

10.1210/me.2007-0029 30 MengX.LiX.XuX.LiP.ChenY.FuX.et al (2019)

Preclinical pharmacology of AZD5363, an inhibitor of AKT: pharmacodynamics, antitumor activity, and correlation of monotherapy activity with genetic background