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Alterations in the energy homeostasis dynamics, i.e., more lipogenic activity and less lipolytic activity, can lead to abnormal fat buildup, causing hypertrophy and/or hyperplasia of adipocytes, and thus obesity [66]

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The addition of vitamin C to the injection further enhances this effect by promoting collagen production, which also contributes to a brighter and more even skin tone

This inhibition is in large part due to the loss of the functional lipoic arm on their E2 subunits, dihydrolipoamide acetyl transferase (DLAT) and dihydrolipoamide succinyl transferase (DLST), respectively, although total DLAT and DLST levels remain steady (Fig