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Abnormal or faulty mechanotransduction may lead to a range of diseases, such as deafness (Lee et al., 2023), cardiovascular disease (Lyon et al., 2015), metabolic defects (Romani et al., 2021), fibrosis (Ostrow and Sachs, 2005), and osteoporosis ( Mechanical signal transduction involves the direct stimulation of mechanically activated (MA) ion channels by mechanical forces applied to the cell membrane, which convert mechanical forces into biochemical signals and thus respond rapidly and efficiently to the excitation of the cell membrane or the activation of intracellular signals (Qin et al., 2021)

Finally, the classification of isoflavonoid compounds as endocrine disruptors is unwarranted

New efforts should focus on whether orally supplemented OTC causes a similar effect, so that treatments can be tailored accordingly

A person who eats enough protein and lifts something heavy a few times a week will finish the run looking leaner at the same scale weight than someone who simply ate less of everything