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Calorie restriction attenuates lipopolysaccharide (LPS)-induced microglial activation in discrete regions of the hypothalamus and the subfornical organ

doi: 10.1146/annurev-nutr-071813-105541 32 KnottnerusSJGBleekerJCWstRCIFerdinandusseSIJlstLWijburgFAet al

As major detoxifying enzymes, they can detoxify and metabolize exogenous toxic substances, and inactivate the endogenous , -unsaturated aldehydes, quinones, epoxides and the hydroperoxides produced during antioxidant or oxidative stress