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Plasma enzyme assay and liver histology Plasma was extracted from whole blood and immediately measured for alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities using a biochemical kit (Diagnostic Chemicals Ltd., Oxford, CT)

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showed that the transcription level of Wnt3a in GMSCs was high, and the CD39-specific inhibitor POM-1 inhibited the expression of Wnt3a and reduced the level of -catenin, ultimately leading to loss of the osteogenic ability of GMSCs