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Products in South Asia often contain appreciable amounts of spices (cardamom, clove, camphor, mint, saffron, pepper) or other plant materials such as betel leaf (Piper betle) and catechu (Acacia catechu)

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Fluoride toothpaste Although the measures used to assess the benefit varied, studies examining the effect of over-the-counter (OTC) fluoride dentifrice on caries incidence in children and adolescents found the fraction of caries prevented ranged from 16% per tooth to 31% per surface versus placebo or no dentifrice, and concluded that fluoride-containing toothpaste was effective in caries control