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It is also required for synthesis of nucleic acid, notably DNA, the metabolism of fatty acids and amino acids in the mitochondria, and in delivering SAMe, the universal methyl donor (16) (30)

Each of us responds differently to medication

Among the key causative agents, anthracyclines, such as doxorubicin (DOX), are particularly notable, as the severe cardiac damage they inducecharacterized by ventricular dilatation, interstitial fibrosis, and progression to HFsignificantly limits their clinical utility [73]

The duration reported by different studies examining the effects of AOX therapy in male infertility is variable ranging from 1 month (120) to 12 months (78)