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PubMed Kim M, Ly SH, Xie Y, Duronio GN, Ford-Roshon D, Hwang JH, Sulahian R, Rennhack JP, So J, Gjoerup O, Talamas JA, Grandclaudon M, Long HW, Doench JG, Sethi NS, Giannakis M, Hahn WC

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[139] demonstrated that all-trans retinoic acid suppressed PI3K/Akt activity and increased the GSK-3-dependent degradation of phosphorylated -catenin, resulting in the differentiation of hepatic CSCs and increasing their sensitivity to docetaxel