foxo4-dri senolytic peptide study 2017 cell alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice The disordered p53 transactivation domain
The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications Senolytics: charting a new course or enhancing existing anti tumor therapies? Cellular Oncology Springer Nature Link FOXO4 DRI: Human Trial Status, Cancer Research & Senolytic Data FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology
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