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4.5 Intranasal administration Drugs delivered to the olfactory region via IN can reach the olfactory bulb and other CNS regions within minutes via intracellular and extracellular pathways along the olfactory nerves or diffusion (especially for lipophilic small molecules), allowing for a higher concentration of the therapeutic agents in the brain compared to the bloodstream

Differential diagnosis: Fatty change/Lipidosisthe cytoplasm of fat cells may be clearer than that of Ito cells

Instead, gently swirl or roll the vial until the powder dissolves completely

In Dermacentor variabilis and Rhipicephalus ( Boophilus ) annulatus , multiple GSTs have also been found [14, 24]