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Schizonts then undergo trophozoite development, which then takes one of two paths: immature trophozoites either transform into mature trophozoite and then schizont causing RBCs rupture, or differentiate into gametocytes (sexual erythrocytic stage), which are released and taken by the mosquito with its blood meal (185)

N -acetyl transferases create mercapturic acid versions of the xenobiotics which are generally more polar and more water soluble than the parental compound

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Wang X, Schoenhals JE, Li A, Valdecanas DR, Ye H, Zang F, Tang C, Tang M, Liu CG, Liu X, Krishnan S, Allison JP, Sharma P, Hwu P, Komaki R, Overwijk WW, Gomez DR, Chang JY , Hahn SM, Cortez MA, Welsh JW