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Understanding these differences between cell types and between vitrified and untreated controls seems difficult, as hypothermia alone affects nearly every investigated biological pathway ( 50 )

For example, one recent study showed that Au NPs with particle sizes below 20 nm could efficiently escape the RES absorption and showed good tumor uptake 32

Dermatologica Sinica 2023, [Epub ahead of print]:[cited 2023 Mar 2021] Available from: Guyatt GH, Oxman AD, Kunz R, Woodcock J, Brozek J, Helfand M, Alonso-Coello P, Falck-Ytter Y, Jaeschke R, Vist G, et al

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