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Description

The SGID IMF was defrosted at room temperature, diluted 1 in 3 in HBSS, filtered (0.45 m PES syringe filters, low protein bind, Sarstedt) and pre-warmed to 37C

Selectivity of NNMT inhibitors Test compounds were screened in biochemical assays for activity against three structurally similar methyltransferases, including catechol-O-methyltransferase (COMT), DNA (cytosine-5)-methyltransferase 1 (DNMT1), and protein arginine methyltransferase 3 (PRMT3)

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