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Epigenetic mechanisms may also be involved in the development of migraine, and understanding environmentally induced genetic changes associated with this disease may eventually guide the development of therapies capable of reversing these pathophysiological changes in gene function

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, 1 1 .In certain embodiments of the methods provided herein, the pharmaceutical composition is administered once a day

Summary: Yes, vitamin B12 is a water-soluble vitamin that dissolves in water and is excreted through urine, though uniquely it can be stored in the liver for several years