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The Research Use Only Disclaimer Is Not Enough This deserves its own section because its the most common misunderstanding in this industry

Store unopened vials at -20C (freezer) and reconstituted solutions at 2-8C (refrigerator) for optimal stability and shelf life

PE-22-28 Safety Considerations# PE-22-28's safety profile is less burdened by mechanism-specific concerns: TREK-1 channels are expressed throughout the body (brain, heart, vasculature, gastrointestinal tract), so systemic TREK-1 blockade could theoretically affect cardiovascular function, pain sensation, and gastrointestinal motility