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140 However, our understanding of tumour hypoxia in HCC is still in its infancy, so we need to continue to delve deeper into the influence of hypoxia on the TME of HCC and on CD8 + T cells, and work to translate this into clinical applications to broaden new therapeutic strategies against HCC

Adaptation to metabolic stress: insights into a paradoxical Q

In situations where clinical findings are inconclusive, laboratory tests or histological examination of scalp biopsies may be warranted to confirm the diagnosis [138,139]

It plays a critical role in the progression of these diseases through its ADP-ribosyl cyclase and cADPR-hydrolase activities