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coli (Huang et al., 2022), compared to the control level of 3.6 mg L 1

Therefore, diabetic metabolic dysregulation critically subverts pulmonary immune resilience by destabilizing surfactant integrity, amplifying infection susceptibility through combined biosynthetic, antimicrobial, and lipidome perturbations

Our in-depth analysis reveals that during the hyperinflammatory phase, the stabilization of HIF-1 and the activation of mTOR drive the metabolic shift towards glycolysis, promoting the cytokine storm