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When we consider a 20% dropout rate, at least 60 patients without missing values would be required

The exclusion of patients with COPD and asthma in key daratumumab studies and the incidence of bronchial hyperreactivity AEs seen in early trials resulted in the recommendation for post-administration prophylaxis with bronchodilators and inhaled corticosteroids in patients with a history of COPD [13, 65]