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These results are reassuring from a safety standpoint and support the use of AOD9604 as a nutraceutical ingredient

In a randomized, placebo-controlled intervention study with more than 900 older participants experiencing psychological distress, daily supplementation with folic acid (400 g) and vitamin B 12 (100 g) for two years did not reduce the occurrence of symptoms of depression despite significantly improving blood folate, vitamin B 12 , and homocysteine levels compared to placebo (109)

they're the variables that make or break your experimental design

Talk to your doctor for dosing instructions that suit your specific hormone and health requirements