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The skin lesions typical of psoriasis arise when this inflammatory cascade causes skin cells to multiply too quickly

Avoid use while pregnant or nursing

But metformin can also affect vitamin B12 absorption, she says

You may benefit from a Vitamin B12 blood test if you follow a vegan or vegetarian diet, are pregnant or breastfeeding (or planning pregnancy), are over age 50, have digestive or absorption issues (such as celiac disease, Crohns disease, or bariatric surgery history), are a heavy drinker, or have methylation-related concerns