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Description

Prasinezumab slows motor progression in rapidly progressing early-stage Parkinsons disease

Total protein amounts were detected in parallel by the BCA assay (Pierce BCA Protein assay Kit) for normalization of glutathione levels

Microglia are initially activated to stage 1 DAM, which are characterized by a downregulation of homeostatic microglial genes including p2ry12 and cx3cr1 , and an upregulation of genes including trem2 , tyrobp and apoe