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166 The levels of both CCR2 and MCP-1/CCL2 mRNA were increased in bronchial epithelium of COPD patients

Primary fibroblasts are easily obtained during muscle or skin biopsy and fibroblasts culture is highly proliferative, providing a renewable source of cells in vitro (Hu et al., 2019)

[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Granados-Soto V, Teran-Rosales F, Rocha-Gonzalez HI, ReyesGarcia G, Medina-Santillan R, Rodriguez-Silverio J, et al

The exact genesis of immunological tolerance is still elusive, but several theories have been proposed since the mid-twentieth century to explain its origin