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Curcumin exerts context-specific autophagy regulation through dual mechanisms: At moderate concentrations (2025 M), it promotes cytoprotective autophagy via inhibition of the mechanistic target of rapamycin (mTOR)-AKT axis (Zhao et al., 2016), evidenced by decreased p-AKT, p-mTOR, and p-P70S6K expression, coupled with increased microtubule-associated protein 1A/1B-light chain 3- II/microtubule-associated protein 1A/1B-light chain 3-I (LC3-II/LC3-I) conversion

Compared to the large volume of literature regarding the impact of ROS on muscle fatigue, evidence that NO production directly contributes to the development of muscle fatigue is sparse

Fixed cells were incubated with primary antibodies overnight at 4 C

Vitamin D analogs differentially control antimicrobial peptide/alarmin expression in psoriasis